We have used dual-energy x-ray absorptiometry (DXA) in evaluation and follo
wup of a patient with osteopetrosis, before and after cord blood transplant
ation. Other methods of follow-up in such cases have been described, but th
e use of DXA has not previously been reported. We have shown that DXA offer
s a safe means of assessing disease progression, the timing of treatment, a
nd response after therapy for osteopetrosis.