Development of an approach to the synthesis of the plakortones

Authors
Semmelhack, MF Shanmugam, P
Citation
Mf. Semmelhack et P. Shanmugam, Development of an approach to the synthesis of the plakortones, TETRAHEDR L, 41(19), 2000, pp. 3567-3571
Citations number
31
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
19
Year of publication
2000
Pages
3567 - 3571
Database
ISI
SICI code
0040-4039(20000506)41:19<3567:DOAATT>2.0.ZU;2-6
Abstract
A general synthesis of the plakortones has been developed by the synthesis of two key sections, with a focus on Pd(II)-promoted preparation of a cis-f used tetrahydrofuranolactone. The key intermediates were obtained in homoch iral form starting from asymmetric epoxidation of an allylic alcohol. (C) 2 000 Elsevier Science Ltd. All rights reserved.