Co(II)-salen-catalyzed highly cis- and enantioselective cyclopropanation

Authors
Niimi, T Uchida, T Irie, R Katsuki, T
Citation
T. Niimi et al., Co(II)-salen-catalyzed highly cis- and enantioselective cyclopropanation, TETRAHEDR L, 41(19), 2000, pp. 3647-3651
Citations number
31
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
19
Year of publication
2000
Pages
3647 - 3651
Database
ISI
SICI code
0040-4039(20000506)41:19<3647:CHCAEC>2.0.ZU;2-N
Abstract
The reactions of styrene derivatives and t-butyl alpha-diazoacetate using ( R,R)-(salen)cobalt(II) complex 6 as a catalyst in the presence of N-methyli midazole gave the corresponding cyclopropanecarboxylates with excellent ena ntio- (>95% ee) and high cis-stereoselectivity (98%) as well as good chemic al yields. (C) 2000 Elsevier Science Ltd. All rights reserved.