The term prostatitis is applied to a series of disorders, ranging from acut
e bacterial infection to chronic pain syndromes, in which the prostate glan
d is inflamed. Patients present with a variety of symptoms, including urina
ry obstruction, fever, myalgias, decreased libido or impotence, painful eja
culation and low-back and perineal pain. Physical examination often fails t
o clarify the cause of the pain. Cultures and microscopic examination of ur
ine and prostatic secretions before and after prostatic massage may help di
fferentiate prostatitis caused by infection from prostatitis with other cau
ses. Because the rate of occult infection is high, a therapeutic trial of a
ntibiotics is often in order even when patients do not appear to have bacte
rial prostatitis. If the patient responds to therapy, antibiotics are conti
nued for at least three to four weeks, although some men require treatment
for several months. A patient who does not respond might be evaluated for c
hronic nonbacterial prostatitis, in which nonsteroidal anti-inflammatory dr
ugs, alpha-blocking agents, anticholinergic agents or other therapies may p
rovide symptomatic relief.