Large-needle aspiration biopsy for the preoperative selection of palpable thyroid nodules diagnosed by fine-needle aspiration as a microfollicular nodule or suspected cancer
A. Carpi et al., Large-needle aspiration biopsy for the preoperative selection of palpable thyroid nodules diagnosed by fine-needle aspiration as a microfollicular nodule or suspected cancer, AM J CLIN P, 113(6), 2000, pp. 872-877
Citations number
27
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research Diagnosis & Treatment
The palpable thyroid nodules with a fine-needle aspiration (FNA) diagnosis
of microfollicular nodule or suspected cancer usually are excised; however;
most of them are proven benign by postoperative histologic examination. We
reviewed the clinical and pathologic data for patients with thyroid nodule
s with an FNA diagnosis of microfollicular nodule or suspected cancer: nodu
les also were examined by large-needle aspiration biopsy (LNAB) to assess w
hether the distinction achieved by LNAB into pure microfollicular or mixed
microfollicular-macrofollicular nodules could be used preoperatively to bet
ter-predict malignancy. One hundred fourteen nodules of this type were exci
sed. The prevalence of cancer was 22% (14/63) among the microfollicular and
4% (2/51) among the microfollicular-macrofollicular nodules at LNAB. These
data indicate that histologic examination of the LNAB specimen can be used
for preoperative selection of thyroid nodules diagnosed by FNA as a microf
ollicular nodule or suspected cancer.