Adult rhabdomyoma: Report of two cases rhabdomyoma of the lip and of the eyelid

We describe two cases of adult rhabdomyoma. One was located in the lip of a 66-year-old woman and was removed because it was clinically suspicious for infiltrating carcinoma. The other arose in the eyelid of a 60-year-old wom an with a glass eye and was initially interpreted as a reactive process due to the prosthesis. Both lesions were composed of cells with oval nuclei an d deeply eosinophilic cytoplasms with occasional cross striations. Immunore activity for desmin and myoglobin excluded the diagnosis of other tumors wi th similar morphology. The unusual association of the eyelid tumor with the prosthesis suggests a role for chronic irritation in the pathogenesis of r habdomyoma.