Chronic anal fissure is the main cause of anal pain and is very common. Man
y treatment modalities have been tried-none is ideal. Recently, topical nit
ric oxide releasing agents and botulin toxin injections have been used, try
ing to replace surgery. No long-term experience is available. Personal expe
rience with 2,108 open, ambulatory, lateral sphincterotomy with follow-up o
f 4-20 years is presented. (C) 2000 by Excerpta Medica, Inc.