Sweet's syndrome in infancy

Background. - Acute febrile neutrophilic dermatosis (Sweet's syndrome) is v ery uncommon in infancy. Systemic corticosteroid treatment is the standard therapy usually leading to dramatic improvement within a few days. Case report, - A seven-month-old female infant was admitted for investigati on of a rash developing over ten days with fever. Physical examination and skin biopsy led to a diagnosis of Sweet's syndrome. The relative inefficien cy of systemic corticotherapy induced the parents to stop all treatment. Conclusion. - This case report allows us: 1) to consider the clinical and b iological features of Sweet's syndrome in infancy; 2) to describe a cortico steroid resistant disease; and 3) to observe the course of a spontaneous ev olution of Sweet's syndrome. (C) 2000 Editions scientifiques et medicales E lsevier SAS.