S. Oie et al., Microbial contamination of in-use lubricants for non-touch urethral catheters in intermittent self-catheterization, BIOL PHAR B, 23(6), 2000, pp. 781-783
There are no reports on microbial contamination of repeatedly used lubrican
t (84-87% glycerin containing 0.02% benzalkonium chloride) for non-touch ur
ethral catheters in intermittent self-catheterization. In this work, we eva
luated microbial contamination of in-use lubricant and its prevention. Betw
een September and December, 1996, microbial contamination and water activit
y of in-use lubricants in sheathed and lubricated nontouch catheters connec
ted to a tube used by 46 outpatients at our hospital was examined. Microbia
l contamination was detected at 5 to 2.6 x 10(8) colony-forming units (CFU)
/ml in 14 (30.4%) of 46 samples. With higher water activity of the lubrican
t (a higher dilution rate of the lubricant with water), a higher concentrat
ion of microbial contamination was observed. In 3 (21.4%) of the 14 patient
s using contaminated lubricant, urine samples show ed the same microbial sp
ecies as those detected in the lubricant. To prevent microbial contaminatio
n of the lubricant, dilution of the lubricant with water, as a result of re
peated use, should be avoided.