T. Aydemir et al., Effects of antioxidant vitamins A, C, E and trace elements Cu, Se on CuZnSOD, GSH-Px, CAT and LPO levels in chicken erythrocytes, CELL BIOC F, 18(2), 2000, pp. 109-115
The biologically damaging effects of reactive oxygen species are controlled
in vivo by a wide spectrum of antioxidant defence mechanisms. Dietary cons
tituents of antioxidant vitamins and trace elements may play an important r
ole in protecting against oxidant damage. The effects of supplementation of
vitamins A, C, E and trace elements Cu and Se on the activities of antioxi
dant enzymes and lipid peroxide levels in chicken erythrocytes were investi
gated depend on the time. CuZnSOD activity and plasma Cu levels in the Cu g
roup were increased by 39 and 37 per cent respectively. CuZnSOD activity in
vitamin C groups was also increased by 20 per cent. The GSH-Px activity in
Se, Se + E and Se + Ca groups was raised by 35, 46 and 69 per cent respect
ively. Also, the GSH-Px activity in the vitamin C group was increased by 33
per cent. Catalase activity in all of these groups was not significantly d
ifferent when compared with controls (p < 0.01). The maximum decrease in LF
O levels of 42 per cent was obtained for the Se + E group. Copyright (C) 20
00 John Wiley & Sons, Ltd.