A practical method for optical resolution of racemic alcohols or esters via lipase-catalyzed transformation and sulfation

Authors
Yamano, T Kikumoto, F Yamamoto, S Miwa, K Kawada, M Ito, T Ikemoto, T Tomimatsu, K Mizuno, Y
Citation
T. Yamano et al., A practical method for optical resolution of racemic alcohols or esters via lipase-catalyzed transformation and sulfation, CHEM LETT, (5), 2000, pp. 448-449
Citations number
7
Categorie Soggetti
Chemistry
Journal title
CHEMISTRY LETTERS
ISSN journal
03667022 → ACNP
Issue
5
Year of publication
2000
Pages
448 - 449
Database
ISI
SICI code
0366-7022(20000505):5<448:APMFOR>2.0.ZU;2-I
Abstract
Optically active esters were conveniently obtained from the corresponding r acemic alcohols or esters by lipase-catalyzed transformation, followed by s ulfation. Sulfation by sulfurtrioxide pyridine complex enabled facile isola tion of optically active esters by extraction instead of laborious column c hromatography. The method would be especially advantageous on a large scale .