Lower extremity deformities associated with thrombocytopenia and absent radius syndrome

The cases of 11 patients with the syndrome of thrombocytopenia and absent r adius (TAR syndrome) who presented at two institutions between 1970 and 199 6 were reviewed. Knee deformities have been well documented in thrombocytop enia and absent radius syndrome, but an inordinate frequency of other lower extremity problems needing orthopaedic attention was seen. Five of the 11 patients with thrombocytopenia and absent radius syndrome studied had knee deformities, but seven of the 11 had 11 other lower extremity deformities. This article documents all of the lower extremity problems seen in the seve n patients with thrombocytopenia and absent radius syndrome with anomalies other than those of the knee.