Antigenic characterization of the nucleocapsid protein of Newcastle disease virus by means of a new panel of monoclonal antibodies

Authors
Panshin, A Shihmanter, E Weisman, Y Orvell, C Kydyrmanov, A Asanov, N Daulbaeva, K Sayatov, M Lipkind, M
Citation
A. Panshin et al., Antigenic characterization of the nucleocapsid protein of Newcastle disease virus by means of a new panel of monoclonal antibodies, COMPAR IMM, 23(3), 2000, pp. 209-220
Citations number
14
Categorie Soggetti
Veterinary Medicine/Animal Health
Journal title
COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES
ISSN journal
01479571 → ACNP
Volume
23
Issue
3
Year of publication
2000
Pages
209 - 220
Database
ISI
SICI code
0147-9571(200007)23:3<209:ACOTNP>2.0.ZU;2-F
Abstract
Nine monoclonal antibodies (MAB) against nucleocapsid protein (NP) of Newca stle disease virus (NDV) have been prepared and characterized. All the MABs were classified into three groups by means of the competitive binding assa y. At least three antigenic sites were delineated on the NP, The Ist site i ncludes two closely located epitopes; the 2nd site includes two related and two distinct epitopes; the 3rd site includes two closely related and one d istinct epitopes. (C) 2000 Elsevier Science Ltd. All rights reserved.