The eosinophil peroxidase gene forms a cluster with the genes for myeloperoxidase and lactoperoxidase on human chromosome 17

Authors
Sakamaki, K Kanda, N Ueda, T Aikawa, E Nagata, S
Citation
K. Sakamaki et al., The eosinophil peroxidase gene forms a cluster with the genes for myeloperoxidase and lactoperoxidase on human chromosome 17, CYTOG C GEN, 88(3-4), 2000, pp. 246-248
Citations number
12
Categorie Soggetti
Molecular Biology & Genetics
Journal title
CYTOGENETICS AND CELL GENETICS
ISSN journal
03010171 → ACNP
Volume
88
Issue
3-4
Year of publication
2000
Pages
246 - 248
Database
ISI
SICI code
0301-0171(2000)88:3-4<246:TEPGFA>2.0.ZU;2-5
Abstract
Eosinophil peroxidase (EPX) is one of a family of mammalian peroxidases tha t includes myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxi dase (TPO). Here we show that the human EPX gene maps to chromosome 17q23.1 , which localizes 34 kb from the LPO and MPO genes. Our results demonstrate that the EPX, LPO, and MPO genes form a cluster on human chromosome 17. Co pyright (C) 2000 S. Karger AG. Basel.