C. Le Chalony et al., Identification and mapping of swine cyclin-dependent kinase inhibitor CDKN2A and CDKN2B exon 2 sequences, CYTOG C GEN, 88(3-4), 2000, pp. 240-243
We have isolated the swine homologs of human CDKN2A and CDKN2B exon 2 seque
nces. As in the human and mouse genomes, the exon 2 sequences of these two
genes present a high level of sequence homology and are tightly linked. Usi
ng fluorescence in situ hybridization, we have mapped swine CDKN2A and CDKN
2B to chromosome 1q25. This confirms the comparative mapping data among man
, mouse, and swine, showing a conserved synteny among chromosome segments 9
p21, 4C3-C6, and 1q25, respectively. Copyright (C) 2000 S. Karger AG,Basel.