Developmental dyslexia: Re-evaluation of the corpus callosum in male adults

Using a new method based upon the measurement of four angles, we analyzed t he corpus callosum of 23 adult male dyslexics and 25 age-matched controls o n MRI sagittal scans. Two out of the four angles measured showed significan t differences between the groups that are consistent with previous findings concerning the size of the corpus callosum in dyslexics. In particular, po sterior regions are concerned, displaying a lowered corpus callosum in dysl exics. These findings are discussed in relation to cortical parietal asymme tries and possible hormonal events, referring to the testosterone hypothesi s, that could occur in utero or in the perinatal period in the dyslexic pop ulation. Copyright (C) 2000 S. Karger AG, Basel.