R. Toscano et al., Synthesis, characterization, and biological activity of N '-trifluoromethanesulfonyl-2-aminopyridine, HETEROAT CH, 11(4), 2000, pp. 308-312
The synthesis, characterization and biological activity of N'-trifluorometh
anesulfonyl-2-aminopyridine in connection with our studies of trifluorometh
anesulfonyl derivatives of the pyridine ring have been achieved. In solutio
n an equilibrium (similar to 50:50%) of the amide and imide tautomeric form
s was observed, while in the solid state only the imide form was present. B
iological tests on the compound showed no effect either upon the growth of
Escherichia coli or on Staphylococcus aureus in the agar diffusion tests; h
owever the growth of Enterococcus faecalis was effectively inhibited. (C) 2
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