Dermatomyositis with splenic and renal infarctions during corticosteroid therapy

A 60-year-old woman was admitted to our hospital with complaints of muscle weakness and erythema on her extremities. Gottron's sign, heliotrope rash, elevation of serum myogenic enzymes, electromyography and magnetic resonanc e imaging findings established a diagnosis of dermatomyositis (DM), She was treated with 60 mg of daily prednisolone. One week later, she suddenly dev eloped splenic and renal infarctions, which were considered to have resulte d from vasculopathy associated with DM, Cyclophosphamide and anticoagulants along with increasing the dosage of corticosteroid were effective, This is the first report describing splenic and renal infarctions in a patient wit h adult-onset DM.