Na. Al-awadi et al., Gas-phase pyrolytic reactions of N-ethyl, N-isopropyl, and N-t-butyl substituted 2-aminopyrazine and 2-aminopyrimidine, INT J CH K, 32(7), 2000, pp. 403-407
The rates of gas-phase elimination of N-ethyl (1), N-isopropyl (2), N-t-but
yl (3) substituted 2-aminopyrazine and N-ethyl (4), N-isopropyl (5), and N-
t-butyl (6) substituted 2-aminopyrimidine have been measured. The compounds
undergo unimolecular first-order pyrolytic reactions. The relative rates o
f the primary:secondary: tertiary alkyl homologues at 600 K are 1 : 14.4: 3
8.0 for the pyrazines and 1 :20.8: 162.5 for the pyrimidines, respectively.
The reactivities of these compounds have been compared with those of the a
lkoxy analogues and with each other. Product analyses, together with the ki
netic data. were used to outline a feasible pathway for the elimination rea
ction of the compounds under study. (C) 2000 John Wiley & Sons, Inc. Int J
Chem Kinet 32: 403-407, 2000.