A case of clear cell carcinoma arising in extragonadal endometriosis

Malignancy developing. in extragonadal endometriosis is rare with the major ity of cases being endometrioid adenocarcinomas. We present a 54-year-old w oman who developed a clear cell carcinoma in her perineum, 25 years after e xcision of a perineal endometrioma in an episiotomy scar. Treatment involve d radiotherapy and surgery, with a view to preserving vaginal function. Whe re benign extragonadal endometriosis occurs, the potential for malignant tr ansformation persists even years after primary treatment.