Je. Wildberger et al., Percutaneous venous thrombectomy with the use of a balloon sheath - First in vitro investigations of a new low-tech concept, INV RADIOL, 35(6), 2000, pp. 352-358
Citations number
38
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging","Medical Research Diagnosis & Treatment
RATIONALE AND OBJECTIVES. TO test mechanical thrombectomy of extensive ilio
femoral and iliocaval thrombi in an in vitro flow model with the use of 12F
and 18F balloon sheaths.
METHODS. Newly developed 12F and 18F sheaths were evaluated in four vessel
models (simulation of femoral, iliofemoral, iliocaval, and caval thrombi by
clotted bovine blood in a flow model). After retrograde insertion of the s
heath and blocking of the vessel proximal to the thrombus by inflating the
balloon, mechanical fragmentation was performed coaxially through the sheat
h lumen by using a 7F pigtail rotation device. With an occlusion balloon ca
theter, residual thrombi were withdrawn to the orifice of the sheath and as
pirated. Twelve silicone tubes occluded by thrombi were recanalized in each
setting. In the latex model, seven recanalizations were performed,
RESULTS. All dots were removed completely within a treatment duration of 2
to 14 minutes. Fluid loss during the procedure was 29.6 to 129.3 mt for the
femoral flow model, 61.9 to 137.2 mt for the iliofemoral model, 74.5 to 16
3.4 mt for the iliocaval model, and 102.7 to 236.7 mt for the caval model.
No fragments were washed downstream. In four settings, small residual throm
bi were attached to the balloon after deflation of the sheath.
CONCLUSIONS. Clot amounts up to 171 g were removed quickly and completely b
y using these large-caliber balloon sheaths, Fluid loss from aspiration was
negligible. Balloon occlusion prevented embolization of thrombus fragments
proximal to the sheath. Further studies are needed to prove the efficacy o
f this technique in vivo.