The families of patients with schizophrenia carry an enormous emotional and
social burden. This article is a historical review of the study of the wel
l siblings of schizophrenic individuals. The early investigations (1950s-19
70s) were based on the theory of familial transmission of schizophrenia and
focused on siblings from the aspect of their susceptibility to the disease
. Many claimed that even siblings who did not develop full blown schizophre
nia still suffered from considerable psychiatric disorders that were attrib
utable to pathological familial psychodynamics. Case control studies were u
sed to explain how some well siblings "escaped" the pathological family net
work. With the introduction of the concept of family burden in the late 196
0s, research shifted to the emotional impact of growing up with a schizophr
enic brother or sister. This was accompanied by the emergence of self-help
groups and published case histories of siblings themselves. In the early 19
80s, the data were essentially descriptive. Investigators studied sibling s
hame, poor self-esteem and feelings of stigmatization. Different patterns o
f coping with the subjective burden were distinguished More recently, great
er efforts have been made to systematically define the variables associated
with the burden experienced by siblings. To answer the many still outstand
ing questions, further studies are needed based on a longitudinal design an
d homogeneous samples. For example: Are sibling's personal relationships ou
tside the family affected? Does the sibling place within the family affect
his or her reaction to the sick brother or sister? Does guilt play a role?
What type of intervention is needed? With the increasing role of the commun
ity in the management of the mentally ill, such research has become very im
portant.