We have assessed the effect of 10:1 lossy (JPEG) compression on six board-c
ertified radiologists' ability to detect three commonly seen abnormalities
on chest radiographs. The study radiographs included 150 chest radiographs
with one of four diagnoses: normal (n = 101), pulmonary nodule (n = 19), in
terstitial lung disease (n = 19), and pneumothorax (n = 11). Before compres
sion, these images were printed on laser film and interpreted in a blinded
fashion by six radiologists. Following an 8-week interval, the images were
reinterpreted on an image display workstation after undergoing 10:1 lossy c
ompression. The results for the compressed images were compared with those
of the uncompressed images using receiver operating characteristic (ROC) an
alyses. Far five of six readers, the diagnostic accuracy was higher for the
uncompressed images than for the compressed images, but the difference was
not significant (P > .1111). Combined readings far the uncompressed images
were also more accurate when compared with the compressed images, but this
difference was also not significant (P = .1430). The sensitivity, specific
ity, and accuracy Values were 81.5%, 89.2%, and 86.7% for the compressed im
ages, respectively, as compared with 78.9%, 94.5%, and 89.3% for the uncomp
ressed images. There was no correlation between the readers' accuracy and t
heir experience with soft-copy interpretation; the extent of radiographic i
nterpretation experience had no correlation with overall interpretation acc
uracy. In conclusion, five of six radiologists had a higher diagnostic accu
racy when interpreting uncompressed chest radiographs versus the same image
s modified by 10:1 lossy compression, but this difference was not statistic
ally significant. Copyright (C) 2000 by W.B. Saunders Company.