A multiscale algorithm for segmenting calcifications from high-resolution mammographic specimen radiographs

We have developed a multiscale algorithm for segmenting breast calcificatio ns from high-resolution specimen radiographs. The algorithm was evaluated u sing 152 mammographic regions of interest digitized at a 15-mu m spatial re solution. The true-positive detection rate was approximately 97.4% with 0.6 7 false-positives per image, and the segmentation error of individual calci fication particles was approximately 5%. The performance of the algorithm i s highly satisfactory. Copyright (C) 2000 by W.B. Saunders Company.