EXPERIMENTAL TRANSMISSION OF NOCTURNALLY PERIODIC WUCHERERIA-BANCROFTI TO INDIAN LEAF MONKEY (PRESBYTIS-ENTELLUS)

Successful experimental transmission of the human lymphatic dwelling n octurnal periodic strain of Wuchereria bancrofti has been achieved fro m man to Indian leaf monkey (Presbytis entellus) through a susceptible strain of Aedes aegypti. The prepatent period varied between 195 and 240 days. Microfilaria (mf) levels were in general low and the peak co unt was attained at 1800 hr. Of the adult worms 5-12.5% were recovered from male langur while females revealed poor (2.54%) recovery. This h ost-parasite model thus makes available the target parasite material i n substantial quantity to work on chemotherapeutic and immunological i nvestigations. (C) 1997 Academic Press.