Individual supramolecular host-guest interactions studied by dynamic single molecule force spectroscopy

Authors
Schonherr, H Beulen, MWJ Bugler, J Huskens, J van Veggel, FCJM Reinhoudt, DN Vancso, GJ
Citation
H. Schonherr et al., Individual supramolecular host-guest interactions studied by dynamic single molecule force spectroscopy, J AM CHEM S, 122(20), 2000, pp. 4963-4967
Citations number
32
Categorie Soggetti
Chemistry & Analysis",Chemistry
Journal title
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
ISSN journal
00027863 → ACNP
Volume
122
Issue
20
Year of publication
2000
Pages
4963 - 4967
Database
ISI
SICI code
0002-7863(20000524)122:20<4963:ISHISB>2.0.ZU;2-5
Abstract
Supramolecular host-guest interactions in aqueous environment were studied by dynamic single molecule force spectroscopy. The unbinding between ferroc ene moieties immobilized on atomic force microscopy tips and beta-cyclodext rin receptors in highly ordered self-assembled monolayers on Au(111) was st udied. The rupture force of individual ferrocene-beta-cyclodextrin complexe s was found to be 56 +/- 10 pN. The value of this unbinding force was indep endent of the unloading rate. This was attributed to the fast (de)complexat ion kinetics of the host-guest complex.