Bite angle effect of bidentate P-N ligands in palladium catalysed allylic alkylation

Authors
van Haaren, RJ Druijven, CJM van Strijdonck, GPF Oevering, H Reek, JNH Kamer, PCJ van Leeuwen, PWNM
Citation
Rj. Van Haaren et al., Bite angle effect of bidentate P-N ligands in palladium catalysed allylic alkylation, J CHEM S DA, 10, 2000, pp. 1549-1554
Citations number
55
Categorie Soggetti
Inorganic & Nuclear Chemistry
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS
ISSN journal
03009246 → ACNP
Volume
10
Year of publication
2000
Pages
1549 - 1554
Database
ISI
SICI code
0300-9246(2000)10:<1549:BAEOBP>2.0.ZU;2-J
Abstract
Two series of new bidentate P-N ligands have been synthesized. Application of these ligands in the palladium catalysed allylic alkylation of crotyl ch loride and cinnamyl chloride leads to the preferential formation of the bra nched product. A larger bite angle of the ligand leads to higher regioselec tivity. Stoichiometric alkylation of the complex [Pd(C4H7){p-MeOC6H4C=N(CH2 )(4)OPPh2}][O3SCF3] proceeds with 88% regioselectivity to the branched prod uct.