Stereoselectivity in the synthesis of conformationally constrained vicinally dihydroxylated cyclic alpha-amino acids

Authors
Hammer, K Wang, J Falck-Pedersen, ML Romming, C Undheim, K
Citation
K. Hammer et al., Stereoselectivity in the synthesis of conformationally constrained vicinally dihydroxylated cyclic alpha-amino acids, J CHEM S P1, 11, 2000, pp. 1691-1695
Citations number
12
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
ISSN journal
0300922X → ACNP
Volume
11
Year of publication
2000
Pages
1691 - 1695
Database
ISI
SICI code
0300-922X(2000)11:<1691:SITSOC>2.0.ZU;2-L
Abstract
Stereoselective syntheses of precursors to vicinal cis-dihydroxy-1-aminocyc lopentane- and -cyclohexane-carboxylic acid methyl esters and their methoxy analogues are described. The chiral products are isolated as pure enantiom ers. The absolute configurations at the new stereogenic centres are establi shed by X-ray analysis.