Citation
Nl. Maidwell et al., On the development of NAD(P)H-sensitive fluorescent probes, J CHEM S P1, 10, 2000, pp. 1541-1546
Citations number
21
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
ISSN journal
0300922X
→ ACNP
Volume
10
Year of publication
2000
Pages
1541 - 1546
Database
ISI
SICI code
0300-922X(2000)10:<1541:OTDONF>2.0.ZU;2-T
Abstract
In contrast to current, multi-reagent assay systems, the development of a s
ingle reagent that can be used to assay NAD(P)H is described. The reagent e
liminates the fluorophore 4-methylumbelliferone from a quinoxalinium adduct
upon reduction and the chemistry of this process is described.