Primary cutaneous CD30-positive large cell lymphoma

Primary cutaneous CD30-positive large cell lymphoma is a recently described entity, recognized by immunohistochemical criteria. Spontaneous regression may occur and although relapses are frequent, most patients have a favoura ble prognosis. We describe a 83-year-old woman with a large ulcerated tumou r on her right forearm, with 2 months evolution. Histological and immunohis tochemical examination revealed a CD30-positive large cell lymphoma. System ic involvement was not detected. The tumour regressed spontaneously. Cutane ous relapses occurred one year later, all with spontaneous regression. Afte r a 2-year follow-up period, the patient is well, without concurrent extrac utaneous disease. This case is in keeping with other reports of spontaneous regression and favourable outcome of this type of cutaneous lymphoma.