Background In 1994, ministers of health of countries of North and South Ame
rica established the goal of measles eradication from the western hemispher
e by 2000. To accomplish this goal, the Pan American Health Organization (P
AHO) developed an enhanced measles vaccination strategy.
Methods PAHO's measles eradication vaccination strategy has evolved into th
ree principal components; a catch-up measles Vaccination campaign, maintena
nce of high vaccination coverage (keep-up), and periodic follow-up measles
vaccination campaigns. ro monitor progress towards measles eradication, mea
sles surveillance has been strengthened, including the laboratory investiga
tion of suspected measles cases. and periodic follow-up To monitor progress
Findings Both the catch-up and follow-up mass campaigns achieved high vacci
nation coverages in the respective targeted age groups. In 1996, only 2109
confirmed measles cases were reported in the Americas. In 1997, there was a
resurgence of measles in the Americas, mostly as a result of a large measl
es outbreak with over 42000 cases, which occurred mainly among unvaccinated
young adults in Sao Paulo State, Brazil. By 1998, there was a reduction in
the number of reported confirmed measles cases, with a total of 14474 case
s. Reduction of cases continued to the end of 1999, with a total of only 28
28 confirmed cases.
Interpretation PAHO's measles eradication strategy has been effective in in
terrupting transmission and maintaining the absence of measles Virus circul
ation in most parts of the Americas. The PAHO experience provides strong ev
idence that with full implementation of an appropriate Vaccination strategy
, measles transmission can be effectively interrupted.