A fraction isolated from Ehrlich ascites carcinoma as an antitumor and differentiating agent against human leukemic cell ML-2

Authors
Sur, P Nandi, N Ghosh, P Ghosh, NC
Citation
P. Sur et al., A fraction isolated from Ehrlich ascites carcinoma as an antitumor and differentiating agent against human leukemic cell ML-2, NEOPLASMA, 47(2), 2000, pp. 114-117
Citations number
8
Categorie Soggetti
Onconogenesis & Cancer Research
Journal title
NEOPLASMA
ISSN journal
00282685 → ACNP
Volume
47
Issue
2
Year of publication
2000
Pages
114 - 117
Database
ISI
SICI code
0028-2685(2000)47:2<114:AFIFEA>2.0.ZU;2-R
Abstract
Lipopolysaccharide fraction isolated from Ehrlich ascites carcinoma (E-LPS) was investigated as an antitumor agent against human leukemia cell ML-2. M arked cell growth inhibition was observed with ML-2 cell accompanied by inh ibition of DNA synthesis and perturbation of cell cycle. Induction of diffe rentiation in treated ML-2 cells was observed as indicated by morphological maturation, NBT reducing activity and indirect immunofluorescence.