No association between TAU haplotype and Alzheimer's disease in populationor clinic based series or in familial disease

Authors
Baker, M Graff-Radford, D DeVrieze, FW Graff-Radford, N Petersen, RC Kokmen, E Boeve, B Myllykangas, L Polvikoski, T Sulkava, R Verkoniemmi, A Tienari, P Haltia, M Hardy, J Hutton, M Perez-Tur, J
Citation
M. Baker et al., No association between TAU haplotype and Alzheimer's disease in populationor clinic based series or in familial disease, NEUROSCI L, 285(2), 2000, pp. 147-149
Citations number
14
Categorie Soggetti
Neurosciences & Behavoir
Journal title
NEUROSCIENCE LETTERS
ISSN journal
03043940 → ACNP
Volume
285
Issue
2
Year of publication
2000
Pages
147 - 149
Database
ISI
SICI code
0304-3940(20000512)285:2<147:NABTHA>2.0.ZU;2-I
Abstract
We and others have previously identified two distinct haplotypes of the TAU gene in Caucasian populations. In this study, we have assessed whether the se haplotypes show an association with Alzheimer's disease in a variety of populations. They do not. These data are consistent with the view that the involvement of TAU in Alzheimer's disease is a downstream event. (C) 2000 E lsevier Science Ireland Ltd. All rights reserved.