Supramolecular chirogenesis in bis(zinc porphyrin): An absolute configuration probe highly sensitive to guest structure

[GRAPHICS] The role of the ligand's structure and absolute configuration in the supram olecular chirality induction in achiral bis(zinc porphyrin) has been studie d. The amines with bulkier substituents resulted in stronger CD signals due to increased helical displacement in the anti conformer. All the amines wi th an R absolute configuration gave a negative first Cotton effect and posi tive second Cotton effect, while the ligands with an S absolute configurati on produced CD signals with opposite signs due to formation of the left and right-handed screw diastereomers, respectively.