Regiocontrol in an intramolecular Schmidt reaction: Total synthesis of (+)-aspidospermidine

Authors
Iyengar, R Schildknegt, K Aube, J
Citation
R. Iyengar et al., Regiocontrol in an intramolecular Schmidt reaction: Total synthesis of (+)-aspidospermidine, ORG LETT, 2(11), 2000, pp. 1625-1627
Citations number
36
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
2
Issue
11
Year of publication
2000
Pages
1625 - 1627
Database
ISI
SICI code
1523-7060(20000601)2:11<1625:RIAISR>2.0.ZU;2-1
Abstract
[GRAPHICS] A total synthesis of (+)-aspidospermidine (1) is described, featuring an in tramolecular Schmidt reaction as the key step. The effects of stereochemist ry and protecting group status on the regia and chemoselectivity of this re action were examined.