Hemophagocytosis complicating Kawasaki disease

A 6-year-old boy developed hemophagocytic syndrome during the recurrent cou rse of Kawasaki disease. Despite the appropriate treatment modalities for K awasaki disease, he developed pancytopenia, marked hepatosplenomegaly, high -grade fever, hyperferritinemia, hypertriglyceremia, and evidence of hemoph agocytosis in the liver biopsy. Although the course was stormy, he responde d well to a combination therapy of corticosteroids, etoposide VP16, and gra nulocyte colony-stimulating factor G-CSF. The clinical course and the treat ment given were compared with the previous reported cases.