HEMOSTATIC PARAMETERS IN PATIENTS WITH PRIMITIVE VENOUS HYPERTENSION

In twenty patients with primitive venous hypertension and in ten healt hy subjects we have determined the plasmatic levels of: Thrombomodulin (TM), beta-Thromboglobulin (beta-TG), D-Dimer (DD), the tissue activa tor of the plasminogen (t-PA) and the inhibitor of the activator of th e plasminogen (PAI-I), The levels of the parameter we studied have sho wn in the patients a significant difference of beta-TG (p<0.01) and PA I-1 (p<0.01) compared to the controls, whereas there was no significan t difference in the other parameters we studied. Our data underline, i n patients with primitive venous hypertension, the importance that the activation of the platelets and the reduction of the potential fibrin olytic can assume, together with the stasis, regarding the onset of th rombotic complications.