K. Jenett-siems et al., Sipandinolide: A butenolide including a novel type of carbon skeleton fromSiparuna andina, PLANTA MED, 66(4), 2000, pp. 384-385
From a lipophilic extract of leaves of Siparuna andina (Monimiaceae), which
exhibited antiplasmodial activity in vitro, two new compounds have been is
olated: sipandinolide (1), a compound with a novel type of carbon skeleton
and (-)-cis-3-acetoxy-4',5,7-trihydroxyflavanone (2). Their structures were
established by spectroscopic methods; 2 showed moderate antiplasmodial act
ivity whereas 1 was inactive.