PROGNOSTIC INDICATORS FOR SURVIVAL AFTER CURATIVE RESECTION FOR PATIENTS WITH CARCINOMA OF THE STOMACH

Citation
Cw. Wu et al., PROGNOSTIC INDICATORS FOR SURVIVAL AFTER CURATIVE RESECTION FOR PATIENTS WITH CARCINOMA OF THE STOMACH, Digestive diseases and sciences, 42(6), 1997, pp. 1265-1269
Citations number
20
Categorie Soggetti
Gastroenterology & Hepatology
ISSN journal
01632116
Volume
42
Issue
6
Year of publication
1997
Pages
1265 - 1269
Database
ISI
SICI code
0163-2116(1997)42:6<1265:PIFSAC>2.0.ZU;2-O
Abstract
This study aims to determine prognostic indicators among patient-, tum or-, and treatment-related factors of gastric cancer patients. A total of 510 patients who underwent curative gastric resection were studied , Univariate analysis of patient-related factors showed a significantl y lower survival in patients with a history of obstruction, hypoalbumi nemia, and anemia, Tumor-related factors including gross appearance, l ocation, and size of tumor; depth of cancer invasion; level, number, a nd frequency of lymph node metastasis; stromal reaction and tumor grow th pattern; and histological classification all significantly affected survival, Surgical treatment related factors such as total or distal subtotal gastrectomy, extent of lymphadenectomy, and combined resectio n of adjacent organ(s) showed a statistically significant adverse infl uence on survival. Multivariate analysis identified only four tumor-re lated factors-number of metastatic lymph nodes, depth of cancer invasi on, stromal reaction, and gross appearance of the tumor-as independent ly affecting survival. These findings suggest that only four tumor-rel ated factors were prognostic indicators in patients with gastric cance r.