Revised structure of antidesmone, an unusual alkaloid from tropical Antidesma plants (Euphorbiaceae)

Authors
Bringmann, G Schlauer, J Rischer, H Wohlfarth, M Muhlbacher, J Buske, A Porzel, A Schmidt, J Adam, G
Citation
G. Bringmann et al., Revised structure of antidesmone, an unusual alkaloid from tropical Antidesma plants (Euphorbiaceae), TETRAHEDRON, 56(23), 2000, pp. 3691-3695
Citations number
11
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
56
Issue
23
Year of publication
2000
Pages
3691 - 3695
Database
ISI
SICI code
0040-4020(20000602)56:23<3691:RSOAAU>2.0.ZU;2-8
Abstract
The structure of antidesmone, an alkaloid from Antidesma membranaceum Mull. Arg. and A. venosum E. Mey. (Euphorbiaceae), was revised to be (S)-4,8-dio xo-3-methoxy-2-methyl-5-n-octyl-1,4,5,6,7,8-hexahydroquinoline [(S)-2], not the isoquinoline derivative 1, as assumed previously. The revision was ini tiated by biosynthetic feeding experiments of one of our groups. (C) 2000 E lsevier Science Ltd. All rights reserved.