Synthesis of isoindolin-1-ones via palladium-catalyzed intermolecular coupling and heteroannulation between 2-iodobenzoyl chloride and imines

Citation
Cs. Cho et al., Synthesis of isoindolin-1-ones via palladium-catalyzed intermolecular coupling and heteroannulation between 2-iodobenzoyl chloride and imines, TETRAHEDR L, 41(20), 2000, pp. 3891-3893
Citations number
10
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
20
Year of publication
2000
Pages
3891 - 3893
Database
ISI
SICI code
0040-4039(20000521)41:20<3891:SOIVPI>2.0.ZU;2-R
Abstract
2-Iodobenzoyl chloride reacts with an array of imines in acetonitrile-metha nol under carbon monoxide pressure in the presence of a catalytic amount of bis(triphenylphosphine)palladium(II) chloride/triphenylphosphine together with triethylamine to afford the corresponding isoindolin-1-ones in moderat e yields. (C) 2000 Elsevier Science Ltd. All rights reserved.