Fischer's base as a protecting group: protection and deprotection of 2-hydroxybenzaldehydes

Citation
Yj. Cho et al., Fischer's base as a protecting group: protection and deprotection of 2-hydroxybenzaldehydes, TETRAHEDR L, 41(20), 2000, pp. 3915-3917
Citations number
22
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
20
Year of publication
2000
Pages
3915 - 3917
Database
ISI
SICI code
0040-4039(20000521)41:20<3915:FBAAPG>2.0.ZU;2-R
Abstract
The hydroxyl and aldehyde groups of 2-hydroxybenzaldehydes were protected b y the reaction with Fischer's base and deprotected by the ozonolysis in met hanol at -78 degrees C to give the corresponding 2-hydroxybenzaldehydes in good to high yields. (C) 2000 Elsevier Science Ltd. All rights reserved.