Ring closing metathesis reactions of isoquinoline and beta-carboline enamines

Authors
Evans, P Grigg, R York, M
Citation
P. Evans et al., Ring closing metathesis reactions of isoquinoline and beta-carboline enamines, TETRAHEDR L, 41(20), 2000, pp. 3967-3970
Citations number
11
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
20
Year of publication
2000
Pages
3967 - 3970
Database
ISI
SICI code
0040-4039(20000521)41:20<3967:RCMROI>2.0.ZU;2-1
Abstract
Ring closing metathesis of enamines derived from isoquinolines and beta-car boline occurs in DCM at room temperature in good yields. The products of ri ng closing metathesis bear close structural relationships to many alkaloida l natural products and are obtained in yields that bear approximate inverse proportionality to the calculated basicity of the enamine starting materia l. (C) 2000 Elsevier Science Ltd. All rights reserved.