Preparative scale synthesis of (S)-2-hydroxypropoxyamine hydrochloride

Authors
Buchalska, E Madura, I Okrasa, K Plenkiewicz, J Zachara, J
Citation
E. Buchalska et al., Preparative scale synthesis of (S)-2-hydroxypropoxyamine hydrochloride, TETRAHEDR-A, 11(8), 2000, pp. 1781-1788
Citations number
20
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
11
Issue
8
Year of publication
2000
Pages
1781 - 1788
Database
ISI
SICI code
0957-4166(20000505)11:8<1781:PSSO(H>2.0.ZU;2-X
Abstract
A simple preparation of (S)-2-hydroxypropoxyamine hydrochloride by baker's yeast reduction of prochiral N-(2-oxopropoxy)phthalimide followed by acid h ydrolysis is described. (C) 2000 Elsevier Science Ltd. All rights reserved.