Enantioselective total syntheses of kudtriol, 5-epi-kudtriol and their C-11 epimers

Authors
Zhou, G Gao, XL Zhang, Z Li, WDZ Li, YL
Citation
G. Zhou et al., Enantioselective total syntheses of kudtriol, 5-epi-kudtriol and their C-11 epimers, TETRAHEDR-A, 11(8), 2000, pp. 1819-1826
Citations number
15
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
11
Issue
8
Year of publication
2000
Pages
1819 - 1826
Database
ISI
SICI code
0957-4166(20000505)11:8<1819:ETSOK5>2.0.ZU;2-V
Abstract
Two approaches for the enantioselective syntheses of naturally occurring ku dtriol 2a and 5-epi-kudtriol 3a as well as their C-ll epimers are presented , both using the Sharpless asymmetric dihydroxylation as the key reaction. Through comparison of the spectral data of natural triols and synthetic sam ples, we could confirm the absolute configuration of the natural triols. (C ) 2000 Elsevier Science Ltd. All rights reserved.