Bleeding problems in patients undergoing segmental liver transplantation

Liver transplantation is associated with a great risk of bleeding, which is of both surgical and medical etiopathogenesis. All phases of the transplan tation are characterized by a complicated and continuously evolving derange ment of pro- and anticoagulant factors, which result in coagulopathy. The m agnitude of this coagulopathy varies between patients and therefore must be corrected on an individual basis. During the different phases of the trans plantation, treatment must be targeted with the aim of controlling the blee ding according to its pathogenesis. This paper analyzes the problems associ ated with the monitoring and correction of coagulation during the different phases of liver transplantation, with specific focus on the idiosyncrasies of segmental liver transplantation. Blood Coagul Fibrinolysis 11 (suppl 1) :S81-S85 (C) 2000 Lippincott Williams & Wilkins.