Recent developments in the encoding and deconvolution of combinatorial libraries

Authors
Barnes, C Balasubramanian, S
Citation
C. Barnes et S. Balasubramanian, Recent developments in the encoding and deconvolution of combinatorial libraries, CURR OP C B, 4(3), 2000, pp. 346-350
Citations number
39
Categorie Soggetti
Biochemistry & Biophysics
Journal title
CURRENT OPINION IN CHEMICAL BIOLOGY
ISSN journal
13675931 → ACNP
Volume
4
Issue
3
Year of publication
2000
Pages
346 - 350
Database
ISI
SICI code
1367-5931(200006)4:3<346:RDITEA>2.0.ZU;2-2
Abstract
The Value of molecular libraries generated by combinatorial methods is larg ely dependent on the ease and ability to deconvolute or decode the structur e of compounds of interest after screening the library. Following the intro duction of promising concepts in the early 1990s, there has been considerab le progress in the development and refinement of methodologies to address t his issue.