The Erve virus: Possible mode of transmission and reservoir

The Erve virus is suspected to cause severe headache in humans, lasting sev eral days (thunderclap headache). Mice are characterized as a probable rese rvoir for the Erve virus. We tested 396 wild mice for Erve virus using an i mmunofluorescence test and found Erve virus antibodies in five cases, showi ng that small mammals form a reservoir for Erve virus. If ticks are the vec tor for the virus, a coincidence with borreliosis should exist. We were una ble to confirm this in a homogeneous cohort of 955 young men, 62 of whom te sted positive for borreliosis, This group did not test positive significant ly more often in the immunofluorescence test than a gender- and age-matched control group.