Background: Alveolar echinococcosis (AE) primarily affects the liver and ex
trahepatic disease is considered the consequence of a secondary infection v
ia metastatic spread from the hepatic focus.
Patients: Two patients with extrahepatic AE without liver involvement are p
resented. The first case is a patient with AE of the spleen and a small pul
monary calcification. In the second case exclusive affection of the spine w
as observed.
Discussion: Various pathogenetic explanations for hepatic omission appear p
lausible: a passage of oncospheres through hepatic sinuses without causing
disease, a passage via lymphatic vessels or via portocaval anastomoses and
the vascular passage in a retrograde fashion. Extrahepatic manifestation of
AE without apparent liver involvement is rare. However, AE should be taken
into account among other differential diagnoses even in cases of extrahepa
tic lesions without liver involvement.