Clinical and histopathological features of colonic stromal tumor in a child

Neoplasms of the colonic submucosa are rare in children. Gastrointestinal s tromal tumors (GISTs) are undifferentiated tumors, usually diagnosed by imm unohistochemistry. We report a LC-year-old girl with a submucosal GIST of t he ascending colon, which was detected by computed tomography. Diagnosis af ter ileocecal resection was established by histology. In addition, sections were examined immunohistochemically, using antibodies against vimentin, de smin, a-smooth muscle actin, S100, neuron-specific enolase, c-kit, and CD34 . Hematoxylin and eosin-stained sections showed interlacing fascicles with occasional palisades of epithelioid and spindle cells. The tumor cells were positive for vimentin and CD34. To our knowledge, this is the first report ed case of colonic stromal tumor in a child.